Human DPP4/CD26 Recombinant Protein (C-Fc) (HB015021)

Name: Human DPP4/CD26 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HB015021
Price: 298 USD
Availability: InStock

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1mg

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HB015021
説明	Recombinant Human CD26/DPP4 Protein, C-Fc (HB015021) expressed in Mammalian Cells, spanning Asn29-Pro766. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
発現システム	Mammalian cells
アクセッション番号	P27487
タンパク質長	Asn29-Pro766
アプリケーション	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種	Homo sapiens (Human)
性質	Recombinant
エンドトキシンレベル	Please contact with the lab for this information.
純度	>90% as determined by SDS-PAGE.
予測分子量	113.70 kDa
形態	Lyophilized
保存バッファー	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
再構成	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	ADABP, ADCP-2, ADCP2, Adenosine deaminase complexing protein 2, CD26, DPP IV, DPP4, Dipeptidyl peptidase 4, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase IV soluble form, EC:3.4.14.5, T-cell activation antigen CD26, TP103
背景	Dipeptidyl peptidase 4 is a ~88 kDa protein. Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. 1. Ikushima, H. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8439-44. PMID: 10900005 2. Durinx, C. et al. (2000) European journal of biochemistry 267, 5608-13. PMID: 10951221 3. Ginés, S. et al. (2002) The Biochemical journal 361, 203-9. PMID: 11772392 4. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217 5. Aertgeerts, K. et al. (2004) Protein science : a publication of the Protein Society 13, 145-54. PMID: 14691230 9. Davoodi, J. et al. (2007) Proteomics 7, 2300-10. PMID: 17549790
注意事項	For research use only