Anti-Human DPPIV/CD26 Recombinant Antibody (SAA0009) (HB015107)

Name: Anti-Human DPPIV/CD26 Recombinant Antibody (SAA0009)
Brand: abinScience
SKU: HB015107
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	HB015107
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG2b, kappa
Clone ID	SAA0009
Clonality	Monoclonal
Target	TP103, Dipeptidyl peptidase IV, ADABP, Dipeptidyl peptidase 4, CD26, DPP4, Dipeptidyl peptidase IV soluble form, Dipeptidyl peptidase IV membrane form, DPP IV, ADCP2, Adenosine deaminase complexing protein 2, ADCP-2, T-cell activation antigen CD26
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P27487
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Dipeptidyl peptidase 4 (CD26/DPP4) is a ~88 kDa protein. Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. 1. Ikushima, H. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8439-44. PMID: 10900005 2. Durinx, C. et al. (2000) European journal of biochemistry 267, 5608-13. PMID: 10951221 3. Ginés, S. et al. (2002) The Biochemical journal 361, 203-9. PMID: 11772392 4. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217 5. Aertgeerts, K. et al. (2004) Protein science : a publication of the Protein Society 13, 145-54. PMID: 14691230 9. Davoodi, J. et al. (2007) Proteomics 7, 2300-10. PMID: 17549790
Note	For research use only.

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Bioactivity

SEC-HPLC detection for Anti-Human CD26/DPP4 Antibody (ABS0753).

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Datasheet

Anti-Human DPPIV/CD26 Recombinant Antibody (SAA0009).pdf

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Anti-Human DPPIV/CD26 Recombinant Antibody (SAA0009) (HB015107)

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