Human CHD4 Recombinant Protein (N-His) (HC562012)

Name: Human CHD4 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC562012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HC562012
Description	Recombinant Human CHD4 Protein, N-His (HC562012) expressed in E. coli, spanning Thr1706-Gln1912. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q14839
Longueur de protéine	Thr1706-Gln1912
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	26.29 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ATP-dependent helicase CHD4, CHD-4, CHD4, Chromodomain-helicase-DNA-binding protein 4, EC:3.6.4.-, Mi-2 autoantigen 218 kDa protein, Mi2-beta
Contexte	ATP-dependent chromatin remodeler CHD4 is a ~218 kDa protein. ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis. 1. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666 2. Farnung, L. et al. (2020) eLife 9. PMID: 32543371 3. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440 4. Sillibourne, JE. et al. (2007) Molecular biology of the cell 18, 3667-80. PMID: 17626165 5. Tong, JK. et al. (1998) Nature 395, 917-21. PMID: 9804427 6. Gong, F. et al. (2015) Genes & development 29, 197-211. PMID: 25593309
Note	For research use only