Anti-Human CHD4 IP Recombinant Antibody (SAA0262) (HC562013)

Name: Anti-Human CHD4 IP Recombinant Antibody (SAA0262)
Brand: abinScience
SKU: HC562013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HC562013

Species reactivity

Human

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG2a

Clone ID

SAA0262

Clonality

Monoclonal

Target

CHD4, Mi2-beta, Chromodomain-helicase-DNA-binding protein 4, CHD-4, Mi-2 autoantigen 218 kDa protein, ATP-dependent helicase CHD4

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q14839

RRID

Anti-Human CHD4 IP Antibody (SAA0262) (abinScience Cat# HC562013, RRID:AB_3729796)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

ATP-dependent chromatin remodeler CHD4 is a ~218 kDa protein. ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis.

1. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666

2. Farnung, L. et al. (2020) eLife 9. PMID: 32543371

3. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440

4. Sillibourne, JE. et al. (2007) Molecular biology of the cell 18, 3667-80. PMID: 17626165

5. Tong, JK. et al. (1998) Nature 395, 917-21. PMID: 9804427

6. Gong, F. et al. (2015) Genes & development 29, 197-211. PMID: 25593309

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CHD4 IP Antibody (SAA0262)

References

Datasheet

Anti-Human CHD4 IP Recombinant Antibody (SAA0262).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CHD4 IP Recombinant Antibody (SAA0262) (HC562013)

Overview

Images

References

Datasheet

SDS

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