Human Gal9/LGALS9 Recombinant Protein (N-Fc) (HT173011)

Name: Human Gal9/LGALS9 Recombinant Protein (N-Fc)
Brand: abinScience
SKU: HT173011
Price: 298 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	HT173011
Описание	Recombinant Human Gal9/LGALS9 Protein, N-Fc (HT173011) expressed in Mammalian Cells, spanning Ala2-Thr355. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	Mammalian cells
Номер доступа	O00182
Длина белка	Ala2-Thr355
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	63.34 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Galectin-9, Gal-9, Ecalectin, Tumor antigen HOM-HD-21, LGALS9
Фон	Galectin-9 (Gal-9) is a ~39 kDa protein. Binds galactosides. Has high affinity for the Forssman pentasaccharide. Ligand for HAVCR2/TIM3. Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death. Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth. 1. Nagae, M. et al. (2008) Journal of molecular biology 375, 119-35. PMID: 18005988 2. Zhu, C. et al. (2005) Nature immunology 6, 1245-52. PMID: 16286920 3. Bi, S. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 10650-5. PMID: 21670307 4. Gieseke, F. et al. (2013) European journal of immunology 43, 2741-9. PMID: 23817958 5. Mengshol, JA. et al. (2010) PloS one 5, e9504. PMID: 20209097 6. Dai, SY. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 2974-81. PMID: 16116184 7. Kojima, R. et al. (2014) PloS one 9, e86106. PMID: 24465902 9. Golden-Mason, L. et al. (2013) Journal of virology 87, 4835-45. PMID: 23408620
Примечание	For research use only.