Human IGF-I/IGF-1 Recombinant Protein (N-Fc) (HY095031)

Name: Human IGF-I/IGF-1 Recombinant Protein (N-Fc)
Brand: abinScience
SKU: HY095031
Price: 298 USD
Availability: InStock

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Número de catálogo	HY095031
Descripción	Recombinant Human IGF1 Protein, N-Fc (HY095031) expressed in Mammalian Cells, spanning Gly49-Ala118. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	Mammalian cells
Número de acceso	P05019
Longitud de proteína	Gly49-Ala118
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	35.23 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	IBP1, IGF-1, IGF-I, IGF1, Insulin-like growth factor 1, Insulin-like growth factor I, MGF, Mechano growth factor, Somatomedin-C
Fondo	Insulin-like growth factor 1 is a ~21 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. 1. Zoidis, E. et al. (2011) Molecular and cellular biochemistry 348, 33-42. PMID: 21076856 2. Shcheglovitov, A. et al. (2013) Nature 503, 267-71. PMID: 24132240 3. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119 4. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760 5. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 3059-69. PMID: 23243309 6. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 19593-603. PMID: 23696648
Nota	For research use only

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Datasheet

Human IGF-I/IGF-1 Recombinant Protein (N-Fc).pdf

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