Anti-Human IGF1 Recombinant Antibody (SAA0432), FITC (HY095117)

Name: Anti-Human IGF1 Recombinant Antibody (SAA0432), FITC
Brand: abinScience
SKU: HY095117
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	HY095117
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0432
Conjugation	FITC
Clonality	Monoclonal
Target	IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
Accession	P05019
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Insulin-like growth factor 1 (IGF1) is a ~21 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. 1. Zoidis, E. et al. (2011) Molecular and cellular biochemistry 348, 33-42. PMID: 21076856 2. Shcheglovitov, A. et al. (2013) Nature 503, 267-71. PMID: 24132240 3. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119 4. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760 5. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 3059-69. PMID: 23243309 6. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 19593-603. PMID: 23696648
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human IGF1 Recombinant Antibody (SAA0432), FITC.pdf

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Anti-Human IGF1 Recombinant Antibody (SAA0432), FITC (HY095117)

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