Anti-Human IGF1 Recombinant Antibody (SAA0432) (HY095107)

Name: Anti-Human IGF1 Recombinant Antibody (SAA0432)
Brand: abinScience
SKU: HY095107
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	HY095107
Species reactivity	Human
Applications	ELISA, FCM, WB
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0432
Clonality	Monoclonal
Target	IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P05019
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Insulin-like growth factor 1 (IGF1) is a ~21 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. 1. Zoidis, E. et al. (2011) Molecular and cellular biochemistry 348, 33-42. PMID: 21076856 2. Shcheglovitov, A. et al. (2013) Nature 503, 267-71. PMID: 24132240 3. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119 4. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760 5. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 3059-69. PMID: 23243309 6. Fujita, M. et al. (2013) The Journal of biological chemistry 288, 19593-603. PMID: 23696648
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human IGF1 Antibody (SAA0432)
Bioactivity

Detects recombinant human IGF1 (Catalog No: HY095011) in indirect ELISA
Western blot

Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: ATGE3001 200ng
Lane 2: 1* loading buffer

References

Datasheet

Anti-Human IGF1 Recombinant Antibody (SAA0432).pdf

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Formula

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Anti-Human IGF1 Recombinant Antibody (SAA0432) (HY095107)

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