Human ROR1 Recombinant Protein (C-His) (HX065011)

Name: Human ROR1 Recombinant Protein (C-His)
Brand: abinScience
SKU: HX065011
Price: 298 USD
Availability: InStock

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50ug
100ug
1mg

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Даташит
SDS

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Каталожный номер	HX065011
Описание	Recombinant Human ROR1 Protein, C-His (HX065011) expressed in Mammalian Cells, spanning Gln30-Tyr406. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	Mammalian cells
Номер доступа	Q01973
Длина белка	Gln30-Tyr406
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Проверенные приложения	WB
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	45.67 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1
Фон	Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling. 1. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443 2. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 27162350 3. Lin, W. et al. (2023) Nature communications 14, 1578. PMID: 36949068
Примечание	For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Recombinant Human ROR1 Protein, C-His
Bioactivity

Detects Zilovertamab in indirect ELISAs.
Bioactivity

Detects Mouse ROR1 Antibody (R11) in indirect ELISAs.
Bioactivity

Detected by Anti-Human ROR1/NTRKR1 Antibody (R12) in indirect ELISA.
Western blot

Detected by Anti-ROR1 monoclonal antibody (Catalog No: HX065016)
Western blot

Detected by Anti-ROR1 monoclonal antibody (Catalog No: HX065307)
Western blot

Detected by Anti-ROR1 monoclonal antibody (Catalog No: HX065307)
Bioactivity

Detected by Nebratamig (Catalog No: HC336146) in indirect ELISA.