Human TMEM59 Recombinant Protein (N-GST & C-His) (HD403022)

Name: Human TMEM59 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HD403022
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HD403022
Description	Recombinant Human TMEM59 Protein, N-GST & C-His (HD403022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q9BXS4
Longueur de protéine	Gly45-Val135
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	C1orf8, Liver membrane-bound protein, TMEM59, Transmembrane protein 59
Contexte	Transmembrane protein 59 is a ~36 kDa protein. Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding. 1. Boada-Romero, E. et al. (2013) The EMBO journal 32, 566-82. PMID: 23376921 2. Boada-Romero, E. et al. (2016) Nature communications 7, 11821. PMID: 27273576 3. Ullrich, S. et al. (2010) The Journal of biological chemistry 285, 20664-74. PMID: 20427278
Note	For research use only

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Human TMEM59 Recombinant Protein (N-GST & C-His).pdf

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