

| Número de catálogo | MC275021 |
|---|---|
| Descripción |
Recombinant Mouse CD150/SLAMF1 Protein, C-Fc (MC275021) expressed in Mammalian Cells, spanning Thr25-Pro242. Purity: >90% by SDS-PAGE.
Highlights
|
| Sistema de expresión | Mammalian cells |
| Número de acceso | Q9QUM4 |
| Longitud de proteína | Thr25-Pro242 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Mus musculus (Mouse) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Peso molecular predicho | 52.52 kDa |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | CD150, CDw150, IPO-3, SLAM, SLAM family member 1, SLAMF1, Signaling lymphocytic activation molecule |
| Fondo | Signaling lymphocytic activation molecule is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAMF1 signaling seem to exist: one depending on SH2D1A (and perhaps SH2D1B) and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. 1. Howie, D. et al. (2002) Blood 100, 2899-907. PMID: 12351401 2. Aversa, G. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 158, 4036-44. PMID: 9126961 3. Latour, S. et al. (2001) Nature immunology 2, 681-90. PMID: 11477403 4. Cannons, JL. et al. (2004) Immunity 21, 693-706. PMID: 15539155 5. Chen, R. et al. (2006) Molecular and cellular biology 26, 5559-68. PMID: 16847311 6. Wang, N. et al. (2004) The Journal of experimental medicine 199, 1255-64. PMID: 15123745 7. Yusuf, I. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 190-202. PMID: 20525889 8. Wang, N. et al. (2006) American journal of respiratory cell and molecular biology 35, 206-10. PMID: 16528012 9. Griewank, K. et al. (2007) Immunity 27, 751-62. PMID: 18031695 |
| Nota | For research use only |



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