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Mouse SLAM/CD150 Recombinant Protein (N-his) (MC275012)

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Vista general
Número de catálogoMC275012
Descripción
Recombinant Mouse CD150/SLAMF1 Protein, N-his (MC275012) expressed in E. coli, spanning Asp31-Cys232. Purity: >90% by SDS-PAGE.
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoQ9QUM4
Longitud de proteínaAsp31-Cys232
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesMus musculus (Mouse)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Peso molecular predicho 24.93 kDa
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosCD150, CDw150, IPO-3, SLAM, SLAM family member 1, SLAMF1, Signaling lymphocytic activation molecule
Fondo

Signaling lymphocytic activation molecule is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAMF1 signaling seem to exist: one depending on SH2D1A (and perhaps SH2D1B) and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

1. Howie, D. et al. (2002) Blood 100, 2899-907. PMID: 12351401
2. Aversa, G. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 158, 4036-44. PMID: 9126961
3. Latour, S. et al. (2001) Nature immunology 2, 681-90. PMID: 11477403
4. Cannons, JL. et al. (2004) Immunity 21, 693-706. PMID: 15539155
5. Chen, R. et al. (2006) Molecular and cellular biology 26, 5559-68. PMID: 16847311
6. Wang, N. et al. (2004) The Journal of experimental medicine 199, 1255-64. PMID: 15123745
7. Yusuf, I. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 190-202. PMID: 20525889
8. Wang, N. et al. (2006) American journal of respiratory cell and molecular biology 35, 206-10. PMID: 16528012
9. Griewank, K. et al. (2007) Immunity 27, 751-62. PMID: 18031695
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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