Mouse CTLA-4 Recombinant Protein (C-His) (MB651011)

Name: Mouse CTLA-4 Recombinant Protein (C-His)
Brand: abinScience
SKU: MB651011
Price: 298 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue	MB651011
Description	Recombinant Mouse CD152/CTLA4 Protein, C-His (MB651011) expressed in Mammalian Cells, spanning Glu36-Phe162. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	Mammalian cells
Numéro d'accès	P09793
Longueur de protéine	Glu36-Phe162
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Cible	HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	17.32 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Contexte	Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).
Note	For research use only.

Images

SDS-PAGE

SDS-PAGE for Recombinant Mouse CD152/CTLA4 Protein, C-His
Bioactivity

Detects Mouse CD152/CTLA4 Antibody (9D9) in indirect ELISAs.
Bioactivity

Detected by Anti-Mouse CD152/CTLA4 Antibody (H11) (Catalog No: MB651107) in indirect ELISA
Bioactivity

Detected by Anti-Mouse CD152/CTLA4 Antibody (9D9) (Catalog No: MB651207) in indirect ELISA
Bioactivity

Immobilized MW630041 Mouse CD80 Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind MB651011 Mouse CD152/CTLA4 Recombinant Protein (C-His), the EC 50 is 250 ng/mL.