Anti-Mouse CD152/CTLA4 Antibody (9D9) (MB651207)

Datasheet Share product Copy info

Price(USD): $

Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet

Overview

Catalog No.	MB651207
Description	Anti-Mouse CD152/CTLA4 Antibody (9D9) [9D9] (MB651207) is a mouse monoclonal antibody detecting CD152 in in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications.
Species reactivity	Mouse
Applications	in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion
Host species	Mouse
Isotype	IgG2b, kappa
Clone ID	9D9
Clonality	Monoclonal
Target	CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P09793
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).
Note	For research use only.

Images

Bioactivity

Detects CD152/CTLA4 in indirect ELISAs.
Bioactivity

Detects recombinant mouse CD152/CTLA4 (Catalog No: MB651011) in indirect ELISA

References

Datasheet

Anti-Mouse CD152/CTLA4 Antibody (9D9).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse CD152/CTLA4 Antibody (9D9) (MB651207)

Overview

Images

References

Datasheet

Quick access

Contact Us