Mouse CTLA-4 Recombinant Protein (C-His) (MB651011)

Name: Mouse CTLA-4 Recombinant Protein (C-His)
Brand: abinScience
SKU: MB651011
Price: 298 USD
Availability: InStock

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50ug
100ug
1mg

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер	MB651011
Описание	Recombinant Mouse CD152/CTLA4 Protein, C-His (MB651011) expressed in Mammalian Cells, spanning Glu36-Phe162. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	Mammalian cells
Номер доступа	P09793
Длина белка	Glu36-Phe162
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Mus musculus (Mouse)
Характер	Recombinant
Цель	HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	17.32 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Фон	Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).
Примечание	For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Recombinant Mouse CD152/CTLA4 Protein, C-His
Bioactivity

Detects Mouse CD152/CTLA4 Antibody (9D9) in indirect ELISAs.
Bioactivity

Detected by Anti-Mouse CD152/CTLA4 Antibody (H11) (Catalog No: MB651107) in indirect ELISA
Bioactivity

Detected by Anti-Mouse CD152/CTLA4 Antibody (9D9) (Catalog No: MB651207) in indirect ELISA
Bioactivity

Immobilized MW630041 Mouse CD80 Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind MB651011 Mouse CD152/CTLA4 Recombinant Protein (C-His), the EC 50 is 250 ng/mL.