Mouse IL-22 Recombinant Protein (C-Fc) (MV999011)

Name: Mouse IL-22 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MV999011
Price: 298 USD
Availability: InStock

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1mg

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Número de catálogo	MV999011
Descripción	Recombinant Mouse IL22 Protein, C-Fc (MV999011) expressed in Mammalian Cells, spanning Leu34-Val179. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	Mammalian cells
Número de acceso	Q9JJY9
Longitud de proteína	Leu34-Val179
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Mus musculus (Mouse)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	44.98 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-22, IL-TIF, IL22, ILTIF, Interleukin-22, ZCYTO18
Fondo	Interleukin-22 is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3. 1. Saxton, RA. et al. (2021) Immunity 54, 660-672.e9. PMID: 33852830 2. Ulu, A. et al. (2022) Toxicology and applied pharmacology 446, 116044. PMID: 35525330 3. Delbue, D. et al. (2021) Frontiers in medicine 8, 656047. PMID: 33912578 4. Weathington, NM. et al. (2014) The Journal of biological chemistry 289, 17610-9. PMID: 24742671
Nota	For research use only