Mouse IL-22 Recombinant Protein (C-Fc) (MV999011)

Name: Mouse IL-22 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: MV999011
Price: 298 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) :

Spécification :

50ug
100ug
1mg

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue	MV999011
Description	Recombinant Mouse IL22 Protein, C-Fc (MV999011) expressed in Mammalian Cells, spanning Leu34-Val179. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	Mammalian cells
Numéro d'accès	Q9JJY9
Longueur de protéine	Leu34-Val179
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mus musculus (Mouse)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	44.98 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-22, IL-TIF, IL22, ILTIF, Interleukin-22, ZCYTO18
Contexte	Interleukin-22 is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3. 1. Saxton, RA. et al. (2021) Immunity 54, 660-672.e9. PMID: 33852830 2. Ulu, A. et al. (2022) Toxicology and applied pharmacology 446, 116044. PMID: 35525330 3. Delbue, D. et al. (2021) Frontiers in medicine 8, 656047. PMID: 33912578 4. Weathington, NM. et al. (2014) The Journal of biological chemistry 289, 17610-9. PMID: 24742671
Note	For research use only