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Mouse RTN4R/NgR1/Nogor Recombinant Protein (C-His) (MP096011)

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  • 1mg
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Vista general
Número de catálogoMP096011
Descripción
Recombinant Mouse RTN4R/NgR1/Nogor Protein, C-His (MP096011) expressed in Mammalian Cells, spanning Cys27-Ser447. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresiónMammalian cells
Número de accesoQ99PI8
Longitud de proteínaCys27-Ser447
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesMus musculus (Mouse)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Peso molecular predicho 48.46 kDa
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosNOGOR, NgR, Nogo receptor, Nogo-66 receptor, RTN4R, Reticulon-4 receptor
Fondo

Reticulon-4 receptor is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR.

1. Fournier, AE. et al. (2001) Nature 409, 341-6. PMID: 11201742
2. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450
3. Kim, JE. et al. (2004) Neuron 44, 439-51. PMID: 15504325
4. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262
5. Nakaya, N. et al. (2012) The Journal of biological chemistry 287, 37171-84. PMID: 22923615
6. Dickendesher, TL. et al. (2012) Nature neuroscience 15, 703-12. PMID: 22406547
7. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200
9. Palandri, A. et al. (2015) Cell death & disease 6, e1876. PMID: 26335717
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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