Mycobacterium tuberculosis Isocitrate lyase/ICL Recombinant Protein (C-Strep) (JN930022)

Name: Mycobacterium tuberculosis Isocitrate lyase/ICL Recombinant Protein (C-Strep)
Brand: abinScience
SKU: JN930022
Price: 211 USD
Availability: InStock

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Numéro de catalogue	JN930022
Description	Recombinant Mycobacterium tuberculosis Isocitrate lyase/ICL Protein, C-Strep (JN930022) expressed in B. subtilis. Purity: >90% as determined by SDS-PAGE.. Highlights ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	B. subtilis
Numéro d'accès	P9WKK7
Longueur de protéine	Met1-His428
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Mycobacterium tuberculosis
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	EC:4.1.3.1, ICL, Isocitrase, Isocitratase, Isocitrate lyase, icl
Contexte	Isocitrate lyase is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route). 1. Sharma, V. et al. (2000) Nature structural biology 7, 663-8. PMID: 10932251 2. McKinney, JD. et al. (2000) Nature 406, 735-8. PMID: 10963599 3. Kumar, R. et al. (2008) Proteins 72, 892-900. PMID: 18275086 4. Moynihan, MM. et al. (2014) Biochemistry 53, 178-87. PMID: 24354272
Note	For research use only

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Mycobacterium tuberculosis Isocitrate lyase/ICL Recombinant Protein (C-Strep).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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