Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Recombinant Antibody (SAA2568) (JN930023)

Name: Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Recombinant Antibody (SAA2568)
Brand: abinScience
SKU: JN930023
Price: 126 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

JN930023

Species reactivity

Mycobacterium tuberculosis

Applications

ELISA, WB

Host species

Human

Isotype

VHH-hFc

Clone ID

SAA2568

Clonality

Monoclonal

Target

EC:4.1.3.1, ICL, Isocitrase, Isocitratase, Isocitrate lyase, icl

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P9WKK7

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Isocitrate lyase (icl1/Isocitrate lyase 1) is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route).

1. Sharma, V. et al. (2000) Nature structural biology 7, 663-8. PMID: 10932251

2. McKinney, JD. et al. (2000) Nature 406, 735-8. PMID: 10963599

3. Kumar, R. et al. (2008) Proteins 72, 892-900. PMID: 18275086

4. Moynihan, MM. et al. (2014) Biochemistry 53, 178-87. PMID: 24354272

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Antibody (SAA2568)

References

Datasheet

Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Recombinant Antibody (SAA2568).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Recombinant Antibody (SAA2568) (JN930023)

Overview

Images

References

Datasheet

SDS

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