

| Каталожный номер | JN930022 |
|---|---|
| Описание |
Recombinant Mycobacterium tuberculosis Isocitrate lyase/ICL Protein, C-Strep (JN930022) expressed in B. subtilis. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | B. subtilis |
| Номер доступа | P9WKK7 |
| Длина белка | Met1-His428 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Mycobacterium tuberculosis |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | EC:4.1.3.1, ICL, Isocitrase, Isocitratase, Isocitrate lyase, icl |
| Фон | Isocitrate lyase is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It could also catalyze the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route). 1. Sharma, V. et al. (2000) Nature structural biology 7, 663-8. PMID: 10932251 2. McKinney, JD. et al. (2000) Nature 406, 735-8. PMID: 10963599 3. Kumar, R. et al. (2008) Proteins 72, 892-900. PMID: 18275086 4. Moynihan, MM. et al. (2014) Biochemistry 53, 178-87. PMID: 24354272 |
| Примечание | For research use only |



Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]
+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский