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| カタログ番号 | HY216016 | ||||
|---|---|---|---|---|---|
| 説明 |
Research Grade amesotatug (HY216016) is a human monoclonal antibody. Suitable for Human.
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| 種反応性 | Human | ||||
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| 宿主種 | Human | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG1, kappa | ||||
| ターゲット | ANX1, ANXA1, Annexin A1, Annexin Ac2-26, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, LPC1, Lipocortin I, Phospholipase A2 inhibitory protein, p35 | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P04083 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Annexin A1 (ANXA1) is a ~38 kDa protein. Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T cells. Promotes the differentiation of T cells into Th1 cells and negatively regulates differentiation into Th2 cells. 1. Arcone, R. et al. (1993) European journal of biochemistry 211, 347-55. PMID: 8425544 2. D'Acquisto, F. et al. (2007) Blood 109, 1095-102. PMID: 17008549 3. McArthur, S. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 4000-10. PMID: 19625660 4. Pepinsky, RB. et al. (1989) The Biochemical journal 263, 97-103. PMID: 2532504 5. Mailliard, WS. et al. (1996) The Journal of biological chemistry 271, 719-25. PMID: 8557678 | ||||
| 注意事項 | For research use only. |
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