Anti-Human ANXA1 Monoclonal Antibody (1A506) (HY216015)

Name: Anti-Human ANXA1 Monoclonal Antibody (1A506)
Brand: abinScience
SKU: HY216015
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HY216015
Description	Anti-Human ANXA1 Monoclonal Antibody (1A506) [1A506] (HY216015) is a mouse monoclonal antibody detecting ANXA1 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A506
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human ANXA1 (Met1-Asn346).
Target	Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35, Annexin Ac2-26, ANXA1
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04083
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Annexin A1 (ANXA1) is a ~38 kDa protein. Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T cells. Promotes the differentiation of T cells into Th1 cells and negatively regulates differentiation into Th2 cells. 1. Arcone, R. et al. (1993) European journal of biochemistry 211, 347-55. PMID: 8425544 2. D'Acquisto, F. et al. (2007) Blood 109, 1095-102. PMID: 17008549 3. McArthur, S. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 4000-10. PMID: 19625660 4. Pepinsky, RB. et al. (1989) The Biochemical journal 263, 97-103. PMID: 2532504 5. Mailliard, WS. et al. (1996) The Journal of biological chemistry 271, 719-25. PMID: 8557678
Note	For research use only.