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| カタログ番号 | HY476026 |
|---|---|
| 説明 |
Anti-Human APC/Activated protein C (TPP-4885/BAY1896502) (HY476026) is a research-grade recombinant antibody targeting Anticoagulant protein C. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2 |
| クローンID | TPP-4885/BAY1896502 |
| ターゲット | Anticoagulant protein C, Vitamin K-dependent protein C, Blood coagulation factor XIV, Autoprothrombin IIA |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P04070 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | TPP-2312, BAY1316786 |
| 背景 | Vitamin K-dependent protein C (APC/Activated protein C) is a ~52 kDa protein. Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. 1. Kovács, KB. et al. (2015) Thrombosis research 135, 718-26. PMID: 25618265 2. Cao, Q. et al. (2025) Nature 639, 816-824. PMID: 39880037 3. Ding, Q. et al. (2015) Blood 125, 2428-34. PMID: 25651845 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107) |
SDS-PAGE for Research Grade Anti-Human APC/Activated protein C (TPP-4885/BAY1896502)
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