Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (ADG106, RUO) (HC336086)

Name: Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (ADG106, RUO)
Brand: abinScience
SKU: HC336086
Price: 370 USD
Availability: InStock

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Numéro de catalogue	HC336086
Description	Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (ADG106, RUO) (HC336086) is a human monoclonal antibody detecting 4-1BB Ligand/TNFSF9.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG
ID de clone	ADG106
Système d'expression	Mammalian cells
Nature	Recombinant
Applications testées	IF
Cible	4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9
Niveau d'endotoxines	< 10 EU/mg as determined by LAL method.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q07011
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ADG-106, ADG106, ADG106
Contexte	Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
Reférences	1. Ma Y, et al. Preclinical characterization and phase 1 results of ADG106 in patients with advanced solid tumors and non-Hodgkin's lymphoma. Cell Rep Med. 2024 Feb 20;5(2):101414. [HC336086]
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD137/TNFRSF9/4-1BB (ADG106)
Immunofluorescence

Immunofluorescence staining of HDLM2 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.

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Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (ADG106, RUO).pdf

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Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (ADG106, RUO) (HC336086)

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