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Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Utomilumab, RUO) (HC336016)

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Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Utomilumab, RUO)

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Utomilumab, RUO)

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Utomilumab, RUO)

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Utomilumab, RUO)

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Spec:

100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.	HC336016
Description	Utomilumab (HC336016) is a research-grade recombinant antibody targeting CD137. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG2-lambda
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q07011
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	PF-05082566, PF-2566, 1417318-27-4
Background	Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects Human CD137/TNFRSF9/4-1BB in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Utomilumab.

References

Datasheet

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Utomilumab, RUO).pdf

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Formula

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Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Utomilumab, RUO)