Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (AGEN 2373, RUO) (HC336106)

Name: Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (AGEN 2373, RUO)
Brand: abinScience
SKU: HC336106
Price: 370 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HC336106
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	AGEN 2373
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q07011
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	AGEN2373, AGEN-2373, AGEN2373
Background	Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
References	1. Claire Galand, et al., AGEN2373 is a conditionally-active agonist antibody targeting the co-stimulatory receptor CD137 for the treatment of human malignancies. Journal of Clinical Oncology, 2019. [HC336106]
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD137/TNFRSF9/4-1BB (AGEN 2373)
Bioactivity

Detects recombinant human CD137/TNFRSF9 (Catalog No: HC336011) in indirect ELISA