

| Каталожный номер | HC336066 |
|---|---|
| Описание |
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (EU101, RUO) (HC336066) is a human monoclonal antibody detecting 4-1BB Ligand/TNFSF9.
|
| Реактивность видов | Human |
| Применения | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG |
| ID клона | EU101 |
| Биологическая активность | EU101 can target and bind to CD137 expressed on various leukocyte subsets, enhance CD137-mediated signaling, induce the proliferation of cytotoxic T lymphocytes and cytokine production, and promote cytotoxic T lymphocyte-mediated anti-tumor immune responses. Meanwhile, it can also induce natural killer cell-mediated tumor cell killing and suppress the immunosuppressive activity of regulatory T cells [1]. |
| Система экспрессии | Mammalian cells |
| Характер | Recombinant |
| Цель | 4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9 |
| Уровень эндотоксинов | < 10 EU/mg as determined by LAL method. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q07011 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | EU101 |
| Фон | Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Anti-Human CD137/TNFRSF9/4-1BB (EU101)




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