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Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (EDO-B278, RUO) (HB058066)

Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (EDO-B278, RUO)
Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (EDO-B278, RUO)
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  • 概要

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  • データシート

  • SDS

概要
カタログ番号HB058066
説明
Anti-Human CD142/F3/TF (EDO-B278) (HB058066) is a research-grade recombinant antibody targeting CD142. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG
クローンIDEDO-B278
発現システム Mammalian cells
ターゲット Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
エンドトキシンレベル < 10 EU/mg
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P13726
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名EDO-B278, EDOB278, EDOB278
背景

Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak).

注意事項 For research use only. Not suitable for clinical or therapeutic use.
イメージ
  • Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (EDO-B278, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CD142/F3/TF (EDO-B278)

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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