Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (MORAb-066, RUO) (HB058056)

Name: Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (MORAb-066, RUO)
Brand: abinScience
SKU: HB058056
Price: 326 USD
Availability: InStock

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Número de catálogo	HB058056
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	MORAb-066
Sistema de expresión	Mammalian cells
Objetivo	Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P13726
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	MORAb-066, MORAb066, MORAb066
Fondo	Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak).
Referencias	1. Pan Z, et al. Characterization of a novel bispecific antibody targeting tissue factor-positive tumors with T cell engagement. Acta Pharm Sin B. 2022 Apr;12(4):1928-1942. [HB058056]
Nota	For research use only. Not suitable for clinical or therapeutic use.