Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (MORAb-066, RUO) (HB058056)

Name: Anti-Human Coagulation factor III/Tissue Factor Reference Antibody (MORAb-066, RUO)
Brand: abinScience
SKU: HB058056
Price: 326 USD
Availability: InStock

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Numéro de catalogue	HB058056
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG
ID de clone	MORAb-066
Système d'expression	Mammalian cells
Cible	Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P13726
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	MORAb-066, MORAb066, MORAb066
Contexte	Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak).
Reférences	1. Pan Z, et al. Characterization of a novel bispecific antibody targeting tissue factor-positive tumors with T cell engagement. Acta Pharm Sin B. 2022 Apr;12(4):1928-1942. [HB058056]
Note	For research use only. Not suitable for clinical or therapeutic use.