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| カタログ番号 | HB159016 |
|---|---|
| 説明 |
Anti-Human L1CAM Reference Antibody (JCAR023, RUO) (HB159016) is a human monoclonal antibody detecting L1CAM. Expressed in Mammalian cells.
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | JCAR023 |
| 発現システム | Mammalian cells |
| 性質 | Recombinant |
| ターゲット | CAML1, Neural cell adhesion molecule L1, NCAM-L1, N-CAM-L1, CD171, MIC5, L1CAM |
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P32004 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | JCAR023 |
| 背景 | Neural cell adhesion molecule L1 (CD171/L1CAM) is a ~140 kDa protein. Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity. |
| 参考文献 | 1. Chen K, et al. mRNA Vaccines Against SARS-CoV-2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids. Adv Funct Mater. 2022 Sep 26;32(39):2204692. [HB159016] |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human CD171/L1CAM (JCAR023)
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