Please ensure Javascript is enabled for purposes of website accessibility
Главная > Продукты > Антитела > Биосимиляры

Anti-Human GITR/TNFRSF18 Reference Antibody (FPA154, RUO) (HV475066)

Anti-Human GITR/TNFRSF18 Reference Antibody (FPA154, RUO)
Anti-Human GITR/TNFRSF18 Reference Antibody (FPA154, RUO)
Цена(USD): --
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
Свяжитесь с нами
  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHV475066
Описание
Anti-Human GITR/TNFRSF18 Reference Antibody (FPA154, RUO) (HV475066) is a human monoclonal antibody detecting GITR/TNFRSF18. Expressed in Mammalian cells.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG
ID клонаFPA154
Биологическая активность FPA154 can potently exert antibody-dependent cell-mediated cytotoxicity against regulatory T cells that highly express GITR [1].
Система экспрессии Mammalian cells
Характер Recombinant
Цель Activation-inducible TNFR family receptor, GITR, TNFRSF18, CD357, Tumor necrosis factor receptor superfamily member 18, AITR, Glucocorticoid-induced TNFR-related protein
Уровень эндотоксинов < 10 EU/mg as determined by LAL method.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q9Y5U5
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияFPA154
Фон

Tumor necrosis factor receptor superfamily member 18 (CD357/GITR) is a ~26 kDa protein. Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Ссылки 1. Susannah D. Barbee, et al. Abstract 613: Development of FPA154, a novel tetravalent anti-GITR antibody, for the treatment of solid tumors. Cancer Res 1 July 2017; 77 (13_Supplement): 613. [HV475066]
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Anti-Human GITR/TNFRSF18 Reference Antibody (FPA154, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human CD357/TNFRSF18/GITR (FPA154)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.

Почта: [email protected]

Список дистрибьюторов