Anti-Human CEACAM6/CD66c Reference Antibody (NOV1803, RUO) (HW494046)

Name: Anti-Human CEACAM6/CD66c Reference Antibody (NOV1803, RUO)
Brand: abinScience
SKU: HW494046
Price: 370 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HW494046
Descripción	Anti-Human CD66c/CEACAM6 (NOV1803) (HW494046) is a research-grade recombinant antibody targeting CD66. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa
ID de clon	NOV1803
Sistema de expresión	Mammalian cells
Aplicaciones probadas	WB
Objetivo	Normal cross-reacting antigen, Carcinoembryonic antigen-related cell adhesion molecule 6, CEACAM6, CD66c, NCA, Non-specific crossreacting antigen
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P40199
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	NOV1803
Fondo	Cell adhesion molecule CEACAM6 (CD66c) is a ~37 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. 1. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 10910050 2. Kuroki, M. et al. (2001) Journal of leukocyte biology 70, 543-50. PMID: 11590190 3. Kuijpers, TW. et al. (1992) The Journal of cell biology 118, 457-66. PMID: 1378450 4. Blumenthal, RD. et al. (2005) Cancer research 65, 8809-17. PMID: 16204051 5. Oikawa, S. et al. (1991) The Journal of biological chemistry 266, 7995-8001. PMID: 2022629 6. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308 7. Yamanaka, T. et al. (1996) Protein expression and purification 7, 438-46. PMID: 8776764
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Imágenes

Western blot

Western blot analysis was performed using anti-CD66c monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD66c (Catalog No: HW494012)
Lane 2: negative control
Bioactivity

Detects recombinant human CD66c/CEACAM6 (Catalog No: HW494012) in indirect ELISA