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Anti-Human EMP2 Reference Antibody (PG-101, RUO) (HX012016)

Anti-Human EMP2 Reference Antibody (PG-101, RUO)
Anti-Human EMP2 Reference Antibody (PG-101, RUO)
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概要
カタログ番号HX012016
説明
Anti-Human EMP2 (PG-101) (HX012016) is a research-grade recombinant antibody targeting Epithelial membrane protein 2. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG
クローンIDPG-101
発現システム Mammalian cells
ターゲット Epithelial membrane protein 2, EMP2, Protein XMP, XMP, EMP-2
エンドトキシンレベル < 10 EU/mg
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P54851
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名PG-101, PG101, PG101
背景

Epithelial membrane protein 2 (EMP2) is a ~19 kDa protein. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and formation of lipid rafts bearing GPI-anchor proteins.

1. Gee, HY. et al. (2014) American journal of human genetics 94, 884-90. PMID: 24814193
2. Wadehra, M. et al. (2005) Developmental biology 287, 336-45. PMID: 16216233
3. Morales, SA. et al. (2013) Investigative ophthalmology & visual science 54, 2367-72. PMID: 23439602
4. Fu, M. et al. (2011) PloS one 6, e19945. PMID: 21637765
5. Morales, SA. et al. (2012) Experimental eye research 102, 10-6. PMID: 22728127
6. Morales, SA. et al. (2009) Investigative ophthalmology & visual science 50, 4949-56. PMID: 19494199
7. Wilson, HL. et al. (2002) The Journal of biological chemistry 277, 34017-23. PMID: 12107182
8. Gordon, LK. et al. (2013) Oncogene 32, 5369-76. PMID: 23334331
9. Wadehra, M. et al. (2006) Developmental biology 292, 430-41. PMID: 16487956
注意事項 For research use only. Not suitable for clinical or therapeutic use.
イメージ
  • Anti-Human EMP2 Reference Antibody (PG-101, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human EMP2 Reference Antibody (PG-101, RUO)

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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