Anti-Human Coagulation Factor VII Reference Antibody (12D10-Fab, RUO) (HY060013)

Name: Anti-Human Coagulation Factor VII Reference Antibody (12D10-Fab, RUO)
Brand: abinScience
SKU: HY060013
Price: 370 USD
Availability: InStock

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Especificación:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

Número:

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Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HY060013

Descripción

Anti-Human F7 (12D10-Fab) (HY060013) is a research-grade recombinant antibody targeting F7. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Reactividad de especies

Human

Aplicaciones

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

Especie huésped

Chimeric

Clonalidad

Monoclonal

Isotipo

Fab-nd-nd

ID de clon

12D10-Fab

Sistema de expresión

Mammalian cells

Objetivo

F7, Proconvertin, SPCA, Serum prothrombin conversion accelerator, Coagulation factor VII, Eptacog alfa

Nivel de endotoxinas

< 10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P08709

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Coagulation factor VII (F7) is a ~51 kDa protein. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

1. Osterud, B. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 5260-4. PMID: 271951

Nota

For research use only. Not suitable for clinical or therapeutic use.

Imágenes

Referencias

Datasheet