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Anti-Human FVIIa Mutant Version (Vatreptacog alfa) Recombinant Antibody (4F5) (HY060033)

Anti-Human FVIIa Mutant Version (Vatreptacog alfa) Recombinant Antibody (4F5)
Anti-Human FVIIa Mutant Version (Vatreptacog alfa) Recombinant Antibody (4F5)
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Overview
Catalog No.HY060033
Species reactivityHuman
ApplicationsELISA, FuncS, SPR
Host speciesMouse
IsotypeIgG2a, kappa
Clone ID4F5
Clonality Monoclonal
Target F7, Coagulation factor VII, FVII, Proconvertin, Serum prothrombin conversion accelerator, SPCA, Eptacog alfa, mutant version of FVIIa, FVIIaDVQ, Vatreptacog alfa, hFVIIa, rFVIIa analog NN1731
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P08709
RRID Anti-Human FVIIa Mutant Version (Vatreptacog alfa) Antibody (4F5) (abinScience Cat# HY060033, RRID:AB_3727168)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate NamesVatreptacog alfa
Background

Coagulation factor VII (FVIIa Mutant Version (FVIIaDVQ)) is a ~51 kDa protein. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

1. Osterud, B. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 5260-4. PMID: 271951
Note For research use only.
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  • Anti-Human FVIIa Mutant Version (Vatreptacog alfa) Recombinant Antibody (4F5)

    SDS-PAGE

    SDS-PAGE for Anti-Human FVIIa Mutant Version (Vatreptacog alfa) Antibody (4F5)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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