Anti-Human F7 Reference Antibody (12D10-Fab, RUO) (HY060013)

Name: Anti-Human F7 Reference Antibody (12D10-Fab, RUO)
Brand: abinScience
SKU: HY060013
Price: 370 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY060013

Description

Anti-Human F7 (12D10-Fab) (HY060013) is a research-grade recombinant antibody targeting F7. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Species reactivity

Human

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Host species

Chimeric

Isotype

Fab-nd-nd

Clone ID

12D10-Fab

Expression system

Mammalian cells

Clonality

Monoclonal

Target

F7, Proconvertin, SPCA, Serum prothrombin conversion accelerator, Coagulation factor VII, Eptacog alfa

Endotoxin level

< 10 EU/mg

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P08709

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Coagulation factor VII (F7) is a ~51 kDa protein. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

1. Osterud, B. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 5260-4. PMID: 271951

Note

For research use only. Not suitable for clinical or therapeutic use.

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References

Datasheet