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Anti-Human Galectin-9 Reference Antibody (LYT-200, RUO) (HT173016)

Anti-Human Galectin-9 Reference Antibody (LYT-200, RUO)
Anti-Human Galectin-9 Reference Antibody (LYT-200, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHT173016
Описание
Anti-Human LGALS9 (LYT-200) (HT173016) is a research-grade recombinant antibody targeting Ecalectin. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG4-kappa
ID клонаLYT-200
Система экспрессии Mammalian cells
Цель Ecalectin, LGALS9, Galectin-9, Gal-9, Tumor antigen HOM-HD-21
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа O00182
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияLYT-200, LYT200, LYT200
Фон

Galectin-9 (Gal-9) is a ~39 kDa protein. Binds galactosides. Has high affinity for the Forssman pentasaccharide. Ligand for HAVCR2/TIM3. Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death. Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.

1. Nagae, M. et al. (2008) Journal of molecular biology 375, 119-35. PMID: 18005988
2. Zhu, C. et al. (2005) Nature immunology 6, 1245-52. PMID: 16286920
3. Bi, S. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 10650-5. PMID: 21670307
4. Gieseke, F. et al. (2013) European journal of immunology 43, 2741-9. PMID: 23817958
5. Mengshol, JA. et al. (2010) PloS one 5, e9504. PMID: 20209097
6. Dai, SY. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 2974-81. PMID: 16116184
7. Kojima, R. et al. (2014) PloS one 9, e86106. PMID: 24465902
9. Golden-Mason, L. et al. (2013) Journal of virology 87, 4835-45. PMID: 23408620
Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Изображения
  • Anti-Human Galectin-9 Reference Antibody (LYT-200, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human LGALS9 (LYT-200)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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