Anti-Human Podocalyxin Like Reference Antibody (MAI1738, RUO) (HT033016)

Name: Anti-Human Podocalyxin Like Reference Antibody (MAI1738, RUO)
Brand: abinScience
SKU: HT033016
Price: 176 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HT033016
説明	Anti-Human PODXL (MAI1738) (HT033016) is a research-grade recombinant antibody targeting PCLP1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1-kappa
クローンID	MAI1738
発現システム	Mammalian cells
ターゲット	PCLP1, Podocalyxin-like protein 1, GCTM-2 antigen, Gp200, PODXL, Podocalyxin, PC, PCLP, PCLP-1
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	O00592
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	MAI1738
背景	Podocalyxin (PODXL) is a ~58 kDa protein. Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis.
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107)

イメージ

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human PODXL (MAI1738).
Western blot

Western blot analysis was performed using anti-PODXL monoclonal antibody at 1µg/ml on various samples.
Lane 1: recombinant human PODXL (Catalog No: HT033012)
Lane 2: negative control