Anti-Human Nogo Reference Antibody (NG-101, RUO) (HP021036)

Name: Anti-Human Nogo Reference Antibody (NG-101, RUO)
Brand: abinScience
SKU: HP021036
Price: 370 USD
Availability: InStock

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概要

カタログ番号	HP021036
説明	Anti-Human Reticulon-4/RTN4 Antibody (NG-101) (HP021036) is a research-grade recombinant antibody targeting RTN-x. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
アイソタイプ	IgG
クローンID	NG-101
発現システム	Mammalian cells
ターゲット	RTN-x, Reticulon-4, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, NOGO, Nogo protein, Neurite outgrowth inhibitor, NSP, Reticulon-5, KIAA0886, RTN4, Foocen
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q9NQC3
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	NG-101, NG101, NG101
背景	Reticulon-4 (RTN4) is a ~129 kDa protein. Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production. They influence nuclear envelope expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. However each isoform have specific functions mainly depending on their tissue expression specificities (Probable). 1. Yamamoto, Y. et al. (2014) The Biochemical journal 458, 69-79. PMID: 24262037 2. Urade, T. et al. (2014) The Kobe journal of medical sciences 60, E57-65. PMID: 25612671 3. Wang, S. et al. (2016) eLife 5. PMID: 27619977 4. Rämö, O. et al. (2016) Scientific reports 6, 35969. PMID: 27786289 5. Christodoulou, A. et al. (2016) Journal of cell science 129, 1552-65. PMID: 26906412
注意事項	For research use only. Not suitable for clinical or therapeutic use.