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Anti-Human Nogo Recombinant Antibody (SAA0170) (HP021107)

Anti-Human Nogo Recombinant Antibody (SAA0170)
Anti-Human Nogo Recombinant Antibody (SAA0170)
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Overview
Catalog No.HP021107
Species reactivityHuman
ApplicationsELISA, FCM, IHC
Host speciesHuman
IsotypeIgG1
Clone IDSAA0170
Clonality Monoclonal
Target RTN-x, Reticulon-4, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, NOGO, Nogo protein, Neurite outgrowth inhibitor, NSP, Reticulon-5, KIAA0886, RTN4, Foocen
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9NQC3
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Reticulon-4 (RTN4) is a ~129 kDa protein. Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production. They influence nuclear envelope expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. However each isoform have specific functions mainly depending on their tissue expression specificities (Probable).

1. Yamamoto, Y. et al. (2014) The Biochemical journal 458, 69-79. PMID: 24262037
2. Urade, T. et al. (2014) The Kobe journal of medical sciences 60, E57-65. PMID: 25612671
3. Wang, S. et al. (2016) eLife 5. PMID: 27619977
4. Rämö, O. et al. (2016) Scientific reports 6, 35969. PMID: 27786289
5. Christodoulou, A. et al. (2016) Journal of cell science 129, 1552-65. PMID: 26906412
Note For research use only.
Images
  • Anti-Human Nogo Recombinant Antibody (SAA0170)

    SDS-PAGE

    SDS-PAGE for Anti-Human Reticulon-4/RTN4 Antibody (SAA0170)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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