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Anti-Human Serpin E1/PAI-1 Reference Antibody (MEDI-579, RUO) (HY185016)

Anti-Human Serpin E1/PAI-1 Reference Antibody (MEDI-579, RUO)
Anti-Human Serpin E1/PAI-1 Reference Antibody (MEDI-579, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHY185016
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1-kappa
ID клонаMEDI-579
Система экспрессии Mammalian cells
Цель PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P05121
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияMEDI-579, MEDI579, MEDI579
Фон

Plasminogen activator inhibitor 1 (SERPINE1/PAI-1) is a ~45 kDa protein. Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.

1. Szabo, R. et al. (2005) The Biochemical journal 390, 231-42. PMID: 15853774
2. Jankun, J. et al. (2007) International journal of molecular medicine 20, 683-7. PMID: 17912461
3. Lee, MH. et al. (1993) Blood 81, 2357-62. PMID: 8481516
4. Fay, WP. et al. (1997) Blood 90, 204-8. PMID: 9207454
5. Anisuzzaman et al. (2011) Biochemical and biophysical research communications 413, 599-604. PMID: 21925150
6. Planus, E. et al. (1997) Journal of cell science 110 ( Pt 9), 1091-8. PMID: 9175705
7. Degryse, B. et al. (2004) The Journal of biological chemistry 279, 22595-604. PMID: 15001579
8. Kjøller, L. et al. (1997) Experimental cell research 232, 420-9. PMID: 9168821
9. Providence, KM. et al. (2008) Archives of dermatological research 300, 303-10. PMID: 18386027
10. Kortlever, RM. et al. (2006) Nature cell biology 8, 877-84. PMID: 16862142
Ссылки 1. Tang Z, et al. Surface immobilization of a protease through an inhibitor-derived affinity ligand: a bioactive surface with defensive properties against an inhibitor. Chem Commun (Camb). 2015 Sep 28;51(75):14263-6. [HY185016]
Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 (LALAPG) Recombinant Isotype Control Antibody (HyHEL-10) (HP688307)
Изображения
  • Anti-Human Serpin E1/PAI-1 Reference Antibody (MEDI-579, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human Serpin E1/PAI-1 Reference Antibody (MEDI-579, RUO)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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