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Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO) (HV811016)

Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO)
Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO)
Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO)
Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO)
Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO)
Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO)
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  • 概要

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概要
カタログ番号HV811016
説明
Enavatuzumab (HV811016) is a research-grade recombinant antibody targeting CD266. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG1-kappa
発現システム Mammalian cells
ターゲット FGF-inducible 14, TNFRSF12A, FN14, CD266, TweakR, Fibroblast growth factor-inducible immediate-early response protein 14, Tweak-receptor, Tumor necrosis factor receptor superfamily member 12A
エンドトキシンレベル < 10 EU/mg
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q9NP84
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名PDL192, 1062149-33-0
背景

Tumor necrosis factor receptor superfamily member 12A (CD266/TNFRSF12A) is a ~13 kDa protein. Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)
イメージ
  • Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Enavatuzumab.

  • Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Enavatuzumab.

  • Anti-Human CD266/TNFRSF12A Reference Antibody (Enavatuzumab, RUO)

    Western blot

    Western blot analysis was performed using anti-CD266/TNFRSF12A monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CD266/TNFRSF12A (Catalog No: HV811011)
    Lane 2: negative control

参考文献
Formula
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