Anti-Human CD266/TNFRSF12A Reference Antibody (BIIB036, RUO) (HV811036)

Name: Anti-Human CD266/TNFRSF12A Reference Antibody (BIIB036, RUO)
Brand: abinScience
SKU: HV811036
Price: 326 USD
Availability: InStock

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Overview

Catalog No.	HV811036
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	BIIB036
Expression system	Mammalian cells
Clonality	Monoclonal
Target	FGF-inducible 14, TNFRSF12A, FN14, CD266, TweakR, Fibroblast growth factor-inducible immediate-early response protein 14, Tweak-receptor, Tumor necrosis factor receptor superfamily member 12A
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9NP84
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BIIB036
Background	Tumor necrosis factor receptor superfamily member 12A (CD266/TNFRSF12A) is a ~13 kDa protein. Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
References	1. Michaelson JS, et al. The anti-Fn14 antibody BIIB036 inhibits tumor growth in xenografts and patient derived primary tumor models and enhances efficacy of chemotherapeutic agents in multiple xenograft models. Cancer Biol Ther. 2012 Jul;13(9):812-21. [HV811036]
Note	For research use only. Not suitable for clinical or therapeutic use.