Anti-Human HGF Reference Antibody (Ficlatuzumab, RUO) (HB191016)

Name: Anti-Human HGF Reference Antibody (Ficlatuzumab, RUO)
Brand: abinScience
SKU: HB191016
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HB191016
Description	Research Grade Ficlatuzumab (HB191016) is a humanized monoclonal antibody detecting SF in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa
Système d'expression	Mammalian cells
Espèces	Human
Cible	SF, HPTA, Hepatopoietin-A, Hepatocyte growth factor, Scatter factor, HGF
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P14210
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	AV-299, SCH 900105, 1174900-84-5
Contexte	Hepatocyte growth factor (SF,HPTA,Hepatopoietin-A,Hepatocyte growth factor,Scatter factor,HGF) is a ~83 kDa protein. Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation. 1. Tolbert, WD. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13264-9. PMID: 20624990 2. Stamos, J. et al. (2004) The EMBO journal 23, 2325-35. PMID: 15167892 3. Hashimoto, T. et al. (2010) The FEBS journal 277, 4888-900. PMID: 20977675
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)