Anti-Human CD7 Reference Antibody (Grisnilimab, RUO) (HY302016)

Name: Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)
Brand: abinScience
SKU: HY302016
Price: 176 USD
Availability: InStock

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Número de catálogo	HY302016
Descripción	Grisnilimab (HY302016) is a research-grade recombinant antibody targeting CD7. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a-Lambda
Sistema de expresión	Mammalian cells
Objetivo	GP40, CD7, T-cell surface antigen Leu-9, T-cell leukemia antigen, TP41, T-cell antigen CD7
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P09564
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	WT1, 2367001-70-3
Fondo	T-cell antigen CD7 is a ~25 kDa protein. Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels. 1. Rabinowich, H. et al. (1994) Journal of immunology (Baltimore, Md. : 1950) 152, 517-26. PMID: 7506726 2. Lyman, SD. et al. (2000) The Journal of biological chemistry 275, 3431-7. PMID: 10652336 3. Carrel, S. et al. (1991) European journal of immunology 21, 1195-200. PMID: 1709867
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)