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Anti-Human CD7 Reference Antibody (Grisnilimab, RUO) (HY302016)

Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)
Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)
Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)
Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)
Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)
Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)
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  • 1mg
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Aperçu
Numéro de catalogueHY302016
Description
Grisnilimab (HY302016) is a research-grade recombinant antibody targeting CD7. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a-Lambda
Système d'expression Mammalian cells
Cible GP40, CD7, T-cell surface antigen Leu-9, T-cell leukemia antigen, TP41, T-cell antigen CD7
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P09564
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsWT1, 2367001-70-3
Contexte

T-cell antigen CD7 is a ~25 kDa protein. Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels.

1. Rabinowich, H. et al. (1994) Journal of immunology (Baltimore, Md. : 1950) 152, 517-26. PMID: 7506726
2. Lyman, SD. et al. (2000) The Journal of biological chemistry 275, 3431-7. PMID: 10652336
3. Carrel, S. et al. (1991) European journal of immunology 21, 1195-200. PMID: 1709867
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)
Images
  • Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)

    Bioactivity

    Detects Human CD7 in indirect ELISAs.

  • Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Grisnilimab.

  • Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD7 Reference Antibody (Grisnilimab, RUO)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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