

| Numéro de catalogue | HF990036 |
|---|---|
| Reactivité des espèces | Human |
| Applications | ELISA, Functional assay, Research in vivo |
| Isotype | Recombinant human Insulin analogue |
| Activité biologique | Insulin cattle is the two-chain polypeptide hormone produced by the β-cells of pancreatic islets. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates glucose uptake into muscle and fat cells by recruiting membrane glucose transporter Glut-4 to cell surface. Insulin cattle has often been used as growth supplement in culturing cells at the concentration ranging from 1 to 10 ug/mL of medium [1]. in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells. |
| Système d'expression | Mammalian cells |
| Cible | INS, Insulin |
| Niveau d'endotoxines | < 10 EU/mg |
| Pureté | >95% purity as determined by SDS-PAGE. |
| Purification | Purified by Nickel column. |
| Numéro d'accès | P01308 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | 2212020-52-3 |
| Contexte | Insulin is a ~11 kDa protein. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| Reférences | 1. Yousefi R, et al. Aspirin-mediated acetylation induces structural alteration and aggregation of bovine pancreaticinsulin. J Biomol Struct Dyn. 2016;34(2):362-75. [HF990036] |
| Note | For research use only. Not suitable for clinical or therapeutic use. |




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