Research Grade Insulin Degludec (HF990046)

Name: Research Grade Insulin Degludec
Brand: abinScience
SKU: HF990046
Price: 424 USD
Availability: InStock

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SDS

Overview

Catalog No.	HF990046
Species reactivity	Human
Applications	ELISA, Functional assay, Research in vivo
Isotype	Recombinant human Insulin analogue
Biological activity	Insulin cattle is the two-chain polypeptide hormone produced by the β-cells of pancreatic islets. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates glucose uptake into muscle and fat cells by recruiting membrane glucose transporter Glut-4 to cell surface. Insulin cattle has often been used as growth supplement in culturing cells at the concentration ranging from 1 to 10 ug/mL of medium [1]. in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells.
Expression system	Mammalian cells
Target	INS, Insulin
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Purified by Nickel column.
Accession	P01308
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	NN1250, NN-1250, 2381089-83-2
Background	Insulin is a ~11 kDa protein. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
References	1. Yousefi R, et al. Aspirin-mediated acetylation induces structural alteration and aggregation of bovine pancreaticinsulin. J Biomol Struct Dyn. 2016;34(2):362-75. [HF990046]
Note	For research use only. Not suitable for clinical or therapeutic use.

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Datasheet

Research Grade Insulin Degludec.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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Research Grade Insulin Degludec (HF990046)

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Datasheet

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